Barbiturates are hypnotic agents. Veronal is | vedclass

Name: Exam Paper Generator | JEE NEET Paper Generator | Vedclass
Brand: Vedclass
Rating: 5 (35 reviews)

Question

(D) The synthesis of Veronal involves the following steps:$1$. Diethyl malonate $(CH_2(CO_2Et)_2)$ reacts with ethyl iodide $(EtI)$ in the presence of

Vedclass · Accepted Answer

Vedclass · Answer

(D) The synthesis of Veronal involves the following steps:$1$. Diethyl malonate $(CH_2(CO_2Et)_2)$ reacts with ethyl iodide $(EtI)$ in the presence of a base $(EtO^-)$ twice to undergo double alkylation at the active methylene carbon,forming diethyl diethylmalonate,$(Et)_2C(CO_2Et)_2$.$2$. This diethyl diethylmalonate then undergoes a condensation reaction with urea $(NH_2CONH_2)$ in the presence of a base to form $5,5-$diethylbarbituric acid,which is known as Veronal.$3$. The structure of Veronal consists of a pyrimidine ring with two ethyl groups at the $5^{th}$ position and two carbonyl groups at the $4^{th}$ and $6^{th}$ positions,with the $2^{nd}$ position also being a carbonyl group.$4$. Comparing this with the given options,the structure corresponding to $5,5-$diethylbarbituric acid is represented by option $D$.

Barbiturates are hypnotic agents. Veronal is a derivative of barbituric acid. It can be synthesized by the following sequence,then the structure of veronal $(P)$ is :
$CH_2(CO_2Et)_2$ $\xrightarrow[EtI]{EtO^-}$ $\xrightarrow[EtI]{EtO^-}$ $\xrightarrow{Urea}$ $(P)$

Similar Questions

The pair whose both species are used in antacid medicinal preparations is

Explain antimicrobial drugs.

Synthetic detergents are more effective in hard water than soaps because

Which of the following is not a local anesthetic?

Which of the following is a local anaesthetic?

Vedclass Test Series

Exam Paper Generator

Online Exam Module

Barbiturates are hypnotic agents. Veronal is a derivative of barbituric acid. It can be synthesized by the following sequence,then the structure of veronal $(P)$ is :$CH_2(CO_2Et)_2$ $\xrightarrow[EtI]{EtO^-}$ $\xrightarrow[EtI]{EtO^-}$ $\xrightarrow{Urea}$ $(P)$